Isotenulin
Product Specifications
CAS Number
10092-04-3
Target
P-gp
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
Isotenulin inhibits the efflux function of P-glycoprotein (P-gp) by stimulating P-glycoprotein ATPase, helping to overcome multidrug resistance (MDR) in cancer cells. It exhibits cytotoxicity in multidrug-resistant cancer cells KB-vin and in sensitive cancer cells HeLaS3. Additionally, Isotenulin acts synergistically with Paclitaxel, Vinblastine, and Doxorubicin.
Smiles
O(C(C)=O)[C@H]1[C@@]2(C)[C@]([C@H](C)C[C@]3([C@]1([C@@H](C)C(=O)O3)[H])[H])(C=CC2=O)[H]
Molecular Formula
C17H22O5
Molecular Weight
306.354
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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