What is the catalog number for Nocarnickelamides B?

The catalog number for Nocarnickelamides B is TN9153.

What sizes are available for Nocarnickelamides B?

Nocarnickelamides B is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Nocarnickelamides B come in?

Nocarnickelamides B is available in 2 different pack sizes.

Is Nocarnickelamides B in stock?

Nocarnickelamides B is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nocarnickelamides B?

Nocarnickelamides B is manufactured by Molfinity.

What is the estimated delivery time for Nocarnickelamides B?

Estimated delivery time for Nocarnickelamides B is approximately 10 business day(s), depending on your location.

Nocarnickelamides B

Product Specifications

Target

Myosin, ROCK

Related Pathways

Cytoskeletal Signaling, Stem Cells, Cell Cycle/Checkpoint

Bioactivity

Nocarnickelamides B (Compound 2) is a linear peptide and an inhibitor of ROCK1/2. It exhibits dual inhibitory activity against ROCK1 and ROCK2, with IC50 values of 14.9 μM and 21.9 μM, respectively. This compound binds to the ATP binding site and inhibits ROCK-mediated cytoskeletal contraction markers, such as myosin light chain activation. Nocarnickelamides B can be utilized in glaucoma research.