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Aselacin A

Product Specifications

CAS Number

156223-06-2

Target

Endothelin Receptor

Related Pathways

GPCR/G Protein

Bioactivity

Aselacin A targets the endothelin-1 receptor (ET-1 Receptor) and inhibits the binding of ET-1 to both ETA and ETB receptors. It effectively impedes the binding of ET-1 to bovine atrial membranes and porcine brain membranes, with IC50 values of 22 μg/mL and 20 μg/mL, respectively. Aselacin A is applicable for cardiovascular disease research.

Smiles

O=C1OC(C)C(NC(=O)C(NC(=O)CCCCCCCC(O)C=CC=CCCCCC)CCC(=O)N)C(=O)NCCC(=O)NC(C(=O)NC(C(=O)NC1)CO)CC2=CNC=3C=CC=CC32

Molecular Formula

C46H68N8O11

Molecular Weight

909.079

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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