Aselacin A
Product Specifications
CAS Number
156223-06-2
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Bioactivity
Aselacin A targets the endothelin-1 receptor (ET-1 Receptor) and inhibits the binding of ET-1 to both ETA and ETB receptors. It effectively impedes the binding of ET-1 to bovine atrial membranes and porcine brain membranes, with IC50 values of 22 ?g/mL and 20 ?g/mL, respectively. Aselacin A is applicable for cardiovascular disease research.
Smiles
O=C1OC(C)C(NC(=O)C(NC(=O)CCCCCCCC(O)C=CC=CCCCCC)CCC(=O)N)C(=O)NCCC(=O)NC(C(=O)NC(C(=O)NC1)CO)CC2=CNC=3C=CC=CC32
Molecular Formula
C46H68N8O11
Molecular Weight
909.079
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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