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Argyrin B

Product Specifications

CAS Number

174423-36-0

Target

Proteasome|||Antibacterial

Related Pathways

Proteases/Proteasome|||Microbiology/Virology|||Ubiquitination

Bioactivity

Argyrin B is a naturally occurring cyclic peptide that acts as a reversible non-competitive inhibitor of the immunoproteasome. It exhibits higher inhibitory selectivity for the ?5i and ?1i sites of the immunoproteasome compared to the ?5c and ?1c sites of the constitutive proteasome, being nearly 20 times more selective for ?1i than for its homolog ?1c. Additionally, Argyrin B possesses antibacterial properties.

Smiles

C(C=1C=2C(NC1)=CC=CC2OC)[C@@H]3NC(=O)[C@H](CC=4C=5C(NC4)=CC=CC5)NC(=O)C=6N=C(SC6)[C@@H](C)NC(=O)CN(C)C(=O)C(=C)NC(=O)[C@@H](CC)NC(=O)CNC3=O

Molecular Formula

C41H46N10O8S

Molecular Weight

838.931

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/315447168607453238/TN9039

Available Sizes

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