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Aphidicolin 17-acetate

Product Specifications

CAS Number

51103-57-2

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

Aphidicolin 17-acetate is a selective inhibitor of eukaryotic DNA polymerase α (DNA polymeraseα) that does not inhibit DNA polymerases β and γ. It significantly suppresses DNA synthesis in sea urchin embryos and HeLa cells in vivo without affecting RNA and protein synthesis.

Smiles

O=C(OCC1(O)CCC23CC1CC3CCC4C(C)(CO)C(O)CCC42C)C

Molecular Formula

C22H36O5

Molecular Weight

380.518

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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