Aphidicolin 17-acetate
Product Specifications
CAS Number
51103-57-2
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
Aphidicolin 17-acetate is a selective inhibitor of eukaryotic DNA polymerase α (DNA polymeraseα) that does not inhibit DNA polymerases β and γ. It significantly suppresses DNA synthesis in sea urchin embryos and HeLa cells in vivo without affecting RNA and protein synthesis.
Smiles
O=C(OCC1(O)CCC23CC1CC3CCC4C(C)(CO)C(O)CCC42C)C
Molecular Formula
C22H36O5
Molecular Weight
380.518
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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