Eutypenes I
Product Specifications
Target
ERK, VEGFR, Akt
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, PI3K/Akt/mTOR signaling, MAPK, Cytoskeletal Signaling
Bioactivity
Eutypenes I (Compound 9) inhibits the secretion of VEGF-A, hampers the activation of VEGFR, and disrupts its downstream Erk/Akt signaling pathway. It also suppresses the migration of HMEC-1 cells and demonstrates anti-angiogenic activity in a Sprague-Dawley rat model.
Smiles
C[C@]12CC[C@@H](C[C@@]1(C(=C)CCC2=O)O)C(C)(C)O
Molecular Formula
C15H24O3
Molecular Weight
252.349
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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