11α-O-Benzoyl-12β-O-acetyltenacigenin B
Selected Variant
TN8146-01
Size: 10 mg
Product Specifications
CAS Number
154022-52-3
Target
P-gp
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
11α-O-Benzoyl-12β-O-acetyltenacigenin B, a derivative of Tenacigenin B from Marsdenia tenacissima, functions as an inhibitor of P-glycoprotein (Pgp) . This compound has demonstrated its ability to counteract multidrug resistance (MDR) associated with the overexpression of P-glycoprotein (Pgp) in HepG2/Dox cells. It shows promise for applications in cancer research.
Smiles
C[C@@]12[C@@]3([C@@]4(O3)[C@]([C@H](OC(=O)C5=CC=CC=C5)[C@H]1OC(C)=O)([C@]6(C)[C@@](CC4)(C[C@@H](O)CC6)[H])[H])CC[C@H]2C(C)=O
Molecular Formula
C30H38O7
Molecular Weight
510.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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Price
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