Batrachotoxin
Product Specifications
CAS Number
23509-16-2
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Batrachotoxin (BTX), a potent neurotoxin and cardiotoxin, is found in the skin of the Colombian dart frog (Phyllobates aurotaenia) . As an activator of sodium channels (sodium channel), it interferes with normal sodium channel closure by binding to voltage-gated sodium channels (sodium channel) on the cell membrane. This interaction causes a continuous influx of sodium ions into the cells, leading to persistent depolarization.
Smiles
C[C@@]12[C@]34C([C@]56[C@](C[C@H]3O)(C([C@@H](OC(=O)C=7C(C)=CNC7C)C)=CC5)CN(C)CCO6)=CC[C@@]1(C[C@](O)(O4)CC2)[H]
Molecular Formula
C31H42N2O6
Molecular Weight
538.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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