Microcolin H
Product Specifications
CAS Number
2408008-21-7
Target
ATG, Autophagy, p62
Related Pathways
Autophagy
Bioactivity
Microcolin H, a marine lipopeptide and phosphatidylinositol transfer protein ligand, targets PITPα/β. It enhances the conversion of LC3I to LC3II and decreases p62 levels in cancer cells, inducing autophagy cell death (Autophagy) . Furthermore, Microcolin H effectively inhibits tumor growth and exhibits anti-proliferative activity in nude mouse subcutaneous tumor models [1].
Smiles
C(=O)([C@H]1N(C([C@@H](N(C([C@@H](NC([C@@H](N(C([C@@H](CCCCCC)C)=O)C)CC(C)C)=O)[C@H](OC(C)=O)C)=O)C)[C@@H](C)C)=O)C[C@@H](O)C1)N2[C@@H](C)C=CC2=O
Molecular Formula
C38H63N5O9
Molecular Weight
733.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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