Halociline

Halociline, a derivative of alkaloids that can be isolated from the marine fungus Penicillium griseofulvum, targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells. This action is potentially mediated by diverse pathways, including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant, and biofilm inhibitory activities [1] [2].