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MAP3K5-IN-1

Product Specifications

CAS Number

2226941-29-1

Target

PKC|||ROCK|||p38 MAPK

Related Pathways

Cell Cycle/Checkpoint|||Stem Cells|||MAPK|||Chromatin/Epigenetic|||Cytoskeletal Signaling

Bioactivity

Compound 7, also known as 3?-O-Demethyl-4?-N-demethyl-4?-N-acetyl-4?-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 ?M for PKC-?, 0.26 ?M for ROCK, and 0.77 ?M for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 ?M [1].

Smiles

C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)CNC6=O)C=8C(N5[C@](O1)(C[C@H](NC(C)=O)[C@H]2O)[H])=CC=CC8

Molecular Formula

C28H24N4O4

Molecular Weight

480.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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