3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone
Product Specifications
CAS Number
125537-92-0
Target
HIV Protease, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Proteases/Proteasome, Microbiology/Virology
Bioactivity
5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev) MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptase. It exhibits cytotoxic activity against P-388 cell lines, it can inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity.
Smiles
COc1c(O)cc(cc1O)-c1cc(=O)c2c(O)c(OC)c(O)cc2o1
Molecular Formula
C17H14O8
Molecular Weight
346.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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