5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone
Product Specifications
CAS Number
1353676-65-9
Target
Estrogen Receptor/ERR
Related Pathways
Endocrinology/Hormones
Bioactivity
5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone demonstrated a strong anti-proliferative effect on ER-positive breast cancer MCF-7 cells in vitro, with an IC50 value of 4.41 μM. It significantly down-regulated the expression of estrogen receptor-α (ER-α) and inhibited tumor growth in the BCAP-37 human breast cancer cell line xenograft model.
Smiles
O=C1C(OC)=C(OC=2C1=C(O)C=C(O)C2CC=C(C)C)C=3C=C(O)C(O)=C(C3)CC=C(C)C
Molecular Formula
C26H28O7
Molecular Weight
452.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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