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Adonixanthin

Product Specifications

CAS Number

4418-73-9

Target

Nrf2, ROS, p38 MAPK, NADPH, Akt, ERK, MMP

Related Pathways

Metabolism, Proteases/Proteasome, MAPK, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Immunology/Inflammation

Bioactivity

Adonixanthin ((3S,3'R) -Adonixanthin) is a carotenoid that acts as an orally active antioxidant and anticancer agent. It demonstrates the ability to inhibit the proliferation and migration of glioblastoma cells and provides cellular protection against various injuries, suppressing increased reactive oxygen species (ROS) production. Adonixanthin safeguards cells from photo-induced damage through antioxidative responses and Nrf2 activation. It can halt glioblastoma progression and improve blood-brain barrier permeability in autologous intracerebral hemorrhage (ICH) models. This compound is applicable in research related to glioblastoma (GBM) and intracerebral hemorrhage (ICH) .

Smiles

C(=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C=1C(C)(C)C[C@H](O)CC1C)\C)\C)/C)/C)\C=2C(C)(C)C[C@H](O)C(=O)C2C

Molecular Formula

C40H54O3

Molecular Weight

582.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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