Adonixanthin
Product Specifications
CAS Number
4418-73-9
Target
Nrf2|||ROS|||p38 MAPK|||NADPH|||Akt|||ERK|||MMP
Related Pathways
Metabolism|||Proteases/Proteasome|||MAPK|||PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Immunology/Inflammation
Bioactivity
Adonixanthin ((3S,3'R) -Adonixanthin) is a carotenoid that acts as an orally active antioxidant and anticancer agent. It demonstrates the ability to inhibit the proliferation and migration of glioblastoma cells and provides cellular protection against various injuries, suppressing increased reactive oxygen species (ROS) production. Adonixanthin safeguards cells from photo-induced damage through antioxidative responses and Nrf2 activation. It can halt glioblastoma progression and improve blood-brain barrier permeability in autologous intracerebral hemorrhage (ICH) models. This compound is applicable in research related to glioblastoma (GBM) and intracerebral hemorrhage (ICH) .
Smiles
C(=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C=1C(C)(C)C[C@H](O)CC1C)\C)\C)/C)/C)\C=2C(C)(C)C[C@H](O)C(=O)C2C
Molecular Formula
C40H54O3
Molecular Weight
582.86
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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