Coccinine
Product Specifications
CAS Number
485-57-4
Target
Serotonin Transporter, P-gp
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
Coccinine ((-) -Coccinine) is a weak inhibitor of SERT with an IC50 of 196.3 μM and a Ki of 106.8 μM, and P-gp with an IC50 of 0.96 mM. It demonstrates significant antitumor activity against various cancer cell lines, including breast cancer (MCF7, Hs578T, MDA-MB-231), colon cancer (HCT-15), and lung cancer (A549) . Additionally, Coccinine is applicable in research involving tumors and neurological disorders.
Smiles
O(C)[C@@H]1C=C2[C@@]3(C=4C(C[N@@](C3)[C@]2(C[C@@H]1O)[H])=CC5=C(C4)OCO5)[H]
Molecular Formula
C17H19NO4
Molecular Weight
301.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
ARP52760_P050 100 µL
FLJ25439 antibody - N-terminal region (ARP52760_P050)
Sign In for Pricing
View Details ![Mouse Monoclonal TDO2 Antibody (OTI2A4) [CoraFluor 1]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP2-74486CL1 0.1 mL
Mouse Monoclonal TDO2 Antibody (OTI2A4) [CoraFluor 1]
Sign In for Pricing
View Details orb3168743 100 µg
Glycine receptor subunit alpha-3 Antibody (Fluoro488)
Sign In for Pricing
View Details K2453803 1.0 µg DNA
TRBV12-1 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details GTR15246979 1 Vial
Lentiviral mouse Slc25a19 shRNA (UAS) - Lentiviral mouse Slc25a19 shRNA (UAS) plasmid
Sign In for Pricing
View Details