Geiparvarin
Product Specifications
CAS Number
36413-91-9
Target
Caspase|||Apoptosis|||COX|||Microtubule Associated|||Monoamine Oxidase
Related Pathways
Cytoskeletal Signaling|||Apoptosis|||Proteases/Proteasome|||Immunology/Inflammation|||Neuroscience
Bioactivity
Geiparvarin is an anticancer agent that acts as an inhibitor of MAO-B (pIC50= 6.84 ?M) . It exerts its antitumor effects by downregulating COX2 expression and inhibiting angiogenesis. Geiparvarin halts the cell cycle at the G1 phase and induces apoptosis in cancer cells. Additionally, it exhibits antimicrotubule activity (Microtubule/Tubulin) and disrupts the cytoskeleton, contributing to its antiproliferative properties. Geiparvarin is of research interest for its potential effects on lung cancer, leukemia, and breast cancer.
Smiles
O(C/C=C(\C)/C=1OC(C)(C)C(=O)C1)C=2C=C3C(=CC2)C=CC(=O)O3
Molecular Formula
C19H18O5
Molecular Weight
326.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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