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Geiparvarin

Product Specifications

CAS Number

36413-91-9

Target

Caspase, Apoptosis, COX, Microtubule Associated, Monoamine Oxidase

Related Pathways

Cytoskeletal Signaling, Apoptosis, Proteases/Proteasome, Immunology/Inflammation, Neuroscience

Bioactivity

Geiparvarin is an anticancer agent that acts as an inhibitor of MAO-B (pIC50= 6.84 μM) . It exerts its antitumor effects by downregulating COX2 expression and inhibiting angiogenesis. Geiparvarin halts the cell cycle at the G1 phase and induces apoptosis in cancer cells. Additionally, it exhibits antimicrotubule activity (Microtubule/Tubulin) and disrupts the cytoskeleton, contributing to its antiproliferative properties. Geiparvarin is of research interest for its potential effects on lung cancer, leukemia, and breast cancer.

Smiles

O(C/C=C(\C)/C=1OC(C)(C)C(=O)C1)C=2C=C3C(=CC2)C=CC(=O)O3

Molecular Formula

C19H18O5

Molecular Weight

326.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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