Cimicifugic acid D
Product Specifications
CAS Number
219986-51-3
Target
Calcium Channel
Related Pathways
Membrane transporter/Ion channel, Metabolism
Bioactivity
Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyl tartaric acid ester that can induce vasorelaxation and an endothelium-dependent relaxation mechanism in pre-constricted rat aortic strips. During norepinephrine-induced contractions in rat aortic strips, Cimicifugic acid D inhibits extracellular Ca2+ influx through receptor-operated Ca2+ channels (ROC), while it does not affect voltage-dependent Ca2+ channels (VDC) or K+-induced contractions.
Smiles
[C@@H]([C@](CC1=CC=C(O)C=C1)(C(O)=O)O)(OC(/C=C/C2=CC(O)=C(O)C=C2)=O)C(O)=O
Molecular Formula
C20H18O10
Molecular Weight
418.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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