(2R,3S) -PD-1/PD-L1-IN-38

(2R,3S) -PD-1/PD-L1-IN-38 (Compound (±) -13e) is an orally active Ah receptor (AhR) antagonist with both in vivo and in vitro anticancer properties. This compound enhances the secretion of INF-? by CD8+ T cells and inhibits PD-1/PD-L1 signaling.