Thienodolin
Product Specifications
CAS Number
149127-27-5
Target
Others, STAT, NF-κB
Related Pathways
NF-κB, Others, JAK/STAT signaling, Stem Cells
Bioactivity
Thienodolin, an alkaloid discovered in S. albogriseolus, enhances root and shoot growth in rice seedlings at a concentration of 4 μM, but at 40 μM, it inhibits growth. It suppresses LPS-induced nitric oxide (NO) production with an IC50 of 17.2 μM, diminishes LPS-induced rises in inducible NO synthase (iNOS) levels, and hinders LPS-induced IκB degradation in RAW 264.7 macrophages.
Smiles
O=C(N)C=1SC=2NC=3C=C(Cl)C=CC3C2C1
Molecular Formula
C11H7ClN2OS
Molecular Weight
250.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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