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Eupolauridine

Product Specifications

CAS Number

58786-39-3

Target

Topoisomerase

Related Pathways

DNA Damage/DNA Repair

Bioactivity

Eupolauridine is a selective DNA topoisomerase II inhibitor, exhibiting an IC50 of 20 ?M against fungal topoisomerase I and 33 ?M for human topoisomerase I. By inhibiting the catalytic activity of topoisomerase II, Eupolauridine stabilizes the enzyme's cleavage complex with DNA, resulting in DNA damage and imparting antifungal activity. [Eupolauridine] holds potential for the study of fungal infectious diseases.

Smiles

N=1C=CC2=CC=NC=3C=4C=CC=CC4C1C23

Molecular Formula

C14H8N2

Molecular Weight

204.23

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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