Eupolauridine
Product Specifications
CAS Number
58786-39-3
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
Eupolauridine is a selective DNA topoisomerase II inhibitor, exhibiting an IC50 of 20 ?M against fungal topoisomerase I and 33 ?M for human topoisomerase I. By inhibiting the catalytic activity of topoisomerase II, Eupolauridine stabilizes the enzyme's cleavage complex with DNA, resulting in DNA damage and imparting antifungal activity. [Eupolauridine] holds potential for the study of fungal infectious diseases.
Smiles
N=1C=CC2=CC=NC=3C=4C=CC=CC4C1C23
Molecular Formula
C14H8N2
Molecular Weight
204.23
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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