Perezone
Product Specifications
CAS Number
3600-95-1
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
Perezone is a sesquiterpene benzoquinone found in the roots of Acourtia species. It inhibits the activity of leukemia cell line K-562 and human glioblastoma cells U-251 (IC50: 6.83 μM) . Perezone enhances the expression of caspase3, 8, and 9 genes associated with apoptosis (Apoptosis), and it also exhibits antioxidant and anti-inflammatory properties.
Smiles
[C@H](CCC=C(C)C)(C)C1=C(O)C(=O)C(C)=CC1=O
Molecular Formula
C15H20O3
Molecular Weight
248.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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