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Manumycin E

Product Specifications

CAS Number

156250-43-0

Target

Antibiotic, Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

Manumycin E exhibits activity against Gram-positive bacteria and Escherichia coli, but has limited effect on other Gram-negative bacteria and none on fungi. It inhibits RAS farnesyltransferase and demonstrates modest cytotoxic activity against the human colorectal cancer cell line [HCT-116].

Smiles

C(=C/C=C/C=C/C(NC=1C(=O)CCC1O)=O)\[C@@]2(O)[C@]3([C@](O3)(C(=O)C(NC(/C=C/C=C/C=C/CCC(C)C)=O)=C2)[H])[H]

Molecular Formula

C30H34N2O7

Molecular Weight

534.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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