Manumycin E
Product Specifications
CAS Number
156250-43-0
Target
Antibiotic, Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
Manumycin E exhibits activity against Gram-positive bacteria and Escherichia coli, but has limited effect on other Gram-negative bacteria and none on fungi. It inhibits RAS farnesyltransferase and demonstrates modest cytotoxic activity against the human colorectal cancer cell line [HCT-116].
Smiles
C(=C/C=C/C=C/C(NC=1C(=O)CCC1O)=O)\[C@@]2(O)[C@]3([C@](O3)(C(=O)C(NC(/C=C/C=C/C=C/CCC(C)C)=O)=C2)[H])[H]
Molecular Formula
C30H34N2O7
Molecular Weight
534.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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