Chloropeptin I

Chloropeptin I is an inhibitor of the binding between gp120 and CD4, with an IC50 of 2.0 μM, and it selectively exhibits anti-human immunodeficiency virus (HIV) activity.

OC1=C2C=3C4=C(C(=CN4)C[C@@H](NC(C(=O)C5=CC(Cl)=C(O)C(Cl)=C5)=O)C(=O)N[C@@H](C(=O)N[C@@]6(C(=C2)C=C1OC=7C=CC(=CC7)C[C@@H](C(N[C@@H](C(O)=O)C8=CC=C(O)C=C8)=O)N(C)C(=O)[C@H](NC6=O)C9=CC(Cl)=C(O)C(Cl)=C9)[H])C%10=CC(Cl)=C(O)C(Cl)=C%10)C=CC3