2-Hydroxyaclacinomycin A
Product Specifications
CAS Number
79127-36-9
Target
DNA/RNA Synthesis, Antibacterial, Antibiotic
Related Pathways
Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair
Bioactivity
2-Hydroxyaclacinomycin A is an anthracycline antibiotic that demonstrates inhibitory activity against leukemia L-1210 cells, with IC50 values for RNA and DNA synthesis of 0.10 μg/mL and 0.95 μg/mL, respectively.
Smiles
O=C1C=2C=C(O)C=C(O)C2C(=O)C=3C(O)=C4C(=CC13)C(C(=O)OC)C(O)(CC)CC4OC5OC(C)C(OC6OC(C)C(OC7OC(C(=O)CC7)C)C(O)C6)C(N(C)C)C5
Molecular Formula
C42H53NO16
Molecular Weight
827.867
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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