Phleomycin E
Product Specifications
CAS Number
11031-13-3
Target
Antibacterial, Antibiotic
Related Pathways
Microbiology/Virology
Bioactivity
Phleomycin E is a peptide-based antibiotic that is effective against Gram-positive and Gram-negative bacteria as well as mycobacteria. It extends the survival time of mice with transplanted Ehrlich ascites carcinoma and shows inhibitory effects on murine pulmonary solid tumors, with an IC50 of 0.31 μg/mL.
Smiles
O=C(OC1C(O)C(OC(CO)C1O)OC2C(OC(C3=CN=CN3)C(NC(=O)C4=NC(=NC(N)=C4C)C(NCC(N)C(=O)N)CC(=O)N)C(=O)NC(C)C(O)C(C(=O)NC(C(=O)NCCC5=NC(C6=NC(=CS6)C(=O)NCCCCNC(=N)NCCCCNC(=N)N)CS5)C(O)C)C)OC(CO)C(O)C2O)N
Molecular Formula
C60H97N23O21S2
Molecular Weight
1540.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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