Eponemycin
Product Specifications
CAS Number
126509-46-4
Target
Antibiotic, DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology
Bioactivity
Eponemycin is an antibiotic with antitumor properties. It exhibits cytotoxicity against cancer cell lines B16-F10, L1210, P388, and HCT-116, with IC50 values of 0.0017, 0.01, 0.031, and 0.0097 μg/mL, respectively. In B16-F10 and mitomycin C, Eponemycin inhibits DNA synthesis, with IC50 values of 0.1 μg/mL and 0.41 μg/mL, respectively.
Smiles
C([C@@H](NC([C@@H](NC(CCCCC(C)C)=O)CO)=O)CC(C)=C)(=O)[C@@]1(CO)CO1
Molecular Formula
C20H34N2O6
Molecular Weight
398.494
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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