Rhetsinine
Product Specifications
CAS Number
526-43-2
Target
Reductase
Related Pathways
Endocrinology/Hormones, Metabolism
Bioactivity
Rhetsinine is an aldose reductase inhibitor identified in Evodia rutaecarpa, with an IC50 value of 24.1 μM. At a concentration of 100 μM, Rhetsinine significantly reduces sorbitol accumulation, achieving an inhibition rate of 79.3%. This compound is applicable in research concerning diabetic complications, such as diabetic neuropathy and retinopathy.
Smiles
O=C(C=1C=CC=CC1NC)N2C(=O)C=3NC=4C=CC=CC4C3CC2
Molecular Formula
C19H17N3O2
Molecular Weight
319.357
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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