Fezolinetant
Product Specifications
UNSPSC Description
Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes.
Target Antigen
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/Fezolinetant.html
Purity
99.19
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
O=C(N1[C@H](C)C2=NN=C(C3=NC(C)=NS3)N2CC1)C4=CC=C(F)C=C4
Molecular Weight
358.39
References & Citations
[1]Fraser GL, et al. The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile LH Secretion and Moderates Levels of Ovarian Hormones Throughout the Menstrual Cycle. Endocrinology. 2015 Nov;156(11):4214-25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19632/Fezolinetant-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19632/Fezolinetant-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
1629229-37-3
Available Sizes
Curated Selection
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