RNF43 Protein, Mouse, Recombinant (hFc)
Product Specifications
Bioactivity
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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