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RNF43 Protein, Mouse, Recombinant (hFc)

Product Specifications

Bioactivity

RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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