LRP-6 Protein, Human, Recombinant (mFc)

Low-density lipoprotein receptor protein 6 (LRP6) is a Wnt co-receptor with essential functions in the Wnt/?-catenin pathway, and mutations in LRP6 gene are linked to many complex human diseases, including metabolic syndrome, cancer, Alzheimer's disease and osteoporosis. LRP-6 interacts closely with PDGF receptor ? and TGF-? receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/?-catenin. LRP-6 Protein, Human, Recombinant (mFc) is expressed in HEK293 Cells. The accession number is O75581-1.