TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)
Product Specifications
Bioactivity
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand) . DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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