MICA Protein, Human, Recombinant (His & Avi), Biotinylated

TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‐like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.