IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated

Interleukin-1 beta (IL-1?) is induced by inflammatory signals in a broad number of immune cell types. IL-1? (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 20.1 kDa and the accession number is P01584.