CEACAM3 Protein, Human, Recombinant (hFc)

The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac.