TNF alpha Protein, Rabbit, Recombinant

Tumor necrosis factor alpha (TNF?) is the prototypic ligand of the TNF superfamily. TNF? forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1, p55R) and TNF-R2 (TNF receptor type 2, p75R) . TNF? is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF? is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.