TPSB2 Protein, Human, Recombinant (His)

Tryptases are Trypsin-like Serine Proteases. ?-Tryptases are the main isoenzymes in mast cells. ?tryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, ?-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, ?-Tryptases are released and participate in provoking inflammatory conditions . ?-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.