IL-18RAP Protein, Human, Recombinant (hFc & His)
Product Specifications
Bioactivity
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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