LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
Product Specifications
Purity
>90%
Bioactivity
Transforming growth factor beta (TGF?) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGF? gene product. Extracellular activation of these complexes is a critical step in regulation of TGF? function in vivo. The TGF?1 LAP is a ligand for the integrin ?v?6 and that ?v?6-expressing cells induce spatially restricted activition of TGF?1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/105617492155564104/TMPJ-00250
Available Sizes
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