Fmoc-PEG1-CH2CH2-NHS ester
Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
1807521-05-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-peg1-ch2ch2-nhs-ester.html
Purity
96.29
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(CCC1=O)=O)CCOCCNC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O
Molecular Formula
C24H24N2O7
Molecular Weight
452.46
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; PEG Linkers
Available Sizes
Frequently Asked Questions
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