Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant (His)

Catalyzes the deamidation of nicotinamide, an early step in the NAD (+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate. Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.0 kDa and the accession number is P53184.