COMMD5 Protein, Rat, Recombinant (His & Myc)
Product Specifications
Bioactivity
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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