Gefitinib-d6
Product Specifications
CAS Number
1228664-49-0
Target
Autophagy|||EGFR
Related Pathways
Autophagy|||Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling
Bioactivity
Gefitinib-d6 is a deuterated compound of Gefitinib. Gefitinib has a CAS number of 184475-35-2. Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM) .
Smiles
C1C2C(=C(N=CN=2)NC2C=CC(F)=C(Cl)C=2)C=C(OC([2H])([2H])C([2H])([2H])C([2H])([2H])N2CCOCC2)C=1OC
Molecular Formula
C22H18D6ClFN4O3
Molecular Weight
452.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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