Crizotinib-d5
Product Specifications
CAS Number
1395950-84-1
Target
ROS Kinase, Autophagy, c-Met/HGFR, ALK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Autophagy
Bioactivity
Crizotinib-d5 is a deuterated compound of Crizotinib. Crizotinib has a CAS number of 877399-52-5. Crizotinib is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.
Smiles
C1(F)C(Cl)=C([C@H](OC2C=C(C3C=NN(C4([2H])C([2H])([2H])CNCC4([2H])[2H])C=3)C=NC=2N)C)C(Cl)=CC=1
Molecular Formula
C21H17D5Cl2FN5O
Molecular Weight
455.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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