Apatinib-d8
Product Specifications
CAS Number
2468771-43-7
Target
Autophagy|||c-RET|||VEGFR|||c-Kit|||Src
Related Pathways
Apoptosis|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Autophagy
Bioactivity
Apatinib-d8 is a deuterated compound of Apatinib. Apatinib has a CAS number of 811803-05-1. Apatinib is an orally bioavailable and specific VEGFR2 inhibitor (IC50: 1 nM) . In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.
Smiles
C(#N)C1(C(C(C(C1([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C2=CC=C(NC(=O)C3=C(NCC=4C=CN=CC4)N=CC=C3)C=C2
Molecular Formula
C24H15D8N5O
Molecular Weight
405.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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